Peptide Therapy in St. Louis, Missouri
What Are Peptides?
Peptide therapy is an evolving area of integrative medicine that uses short chains of amino acids to support the body’s natural healing, metabolic, and regenerative processes. Because peptides work in different ways, their form and delivery can vary. Some peptides are broken down in the digestive tract and are most effective when administered as injections or nasal sprays, while others can be taken orally.
At Health by Design, peptide recommendations are personalized based on your goals, health history, and clinical evaluation. Certain peptides are available directly through our office, while others are prescribed and fulfilled through trusted specialty compounding pharmacies. Commonly used peptides may include metabolic and weight-management peptides such as GLP-1s, as well as regenerative and wellness peptides like Ipamorelin, Sermorelin, BPC-157, TB-500, GHK-Cu, and NAD+. Combination protocols, such as our GLOW and Wolverine stacks, may also be considered to support skin health, recovery, energy, and overall vitality.
Sermorelin vs. Ipamorelin: How They Work
Sermorelin
Sermorelin is a Growth Hormone–Releasing Hormone (GHRH) analog. It stimulates the pituitary gland to produce and release more natural HGH. It works upstream in the hormone cascade, offering a physiologic and highly controlled way to enhance hormone levels.
Ipamorelin
Ipamorelin is a Growth Hormone Secretagogue (GHS) that triggers the release of growth hormone without significantly affecting cortisol or prolactin. It is known for being gentle, well-tolerated, and effective in supporting recovery, fat metabolism, and anti-aging goals.
Why We Often Combine Them
● Sermorelin supports your body’s natural GH production, helping restore a healthy baseline.
● Ipamorelin amplifies the frequency and strength of GH pulses, maximizing how effectively your body releases growth hormone.
● Together, they create a more balanced, steady, and powerful response, delivering better energy, body composition, sleep, and recovery results than either peptide on its own.
Benefits of Peptide Therapy with Semorelin & Ipamorelin
Promotes Natural Growth Hormone Production
Semorelin and Ipamorelin work by signaling the pituitary gland to release growth hormone in a natural, regulated way, supporting overall hormonal balance without suppressing your body’s own systems.
Enhanced Muscle Growth & Lean Body Composition
By increasing GH levels, peptide therapy helps boost muscle protein synthesis, leading to improved muscle tone, strength, and a more favorable body composition with reduced body fat.
Supports Fat Metabolism & Weight Management
Peptides help activate lipolysis, the breakdown of stored fat, which supports fat loss and a healthier metabolism when paired with proper diet and exercise.
Improves Sleep Quality & Recovery
Better deep sleep and restorative rest are commonly reported benefits, as growth hormone release is closely tied to sleep cycles. Improved sleep enhances recovery, energy levels, and cognitive clarity.
Faster Tissue Repair & Physical Recovery
Increased GH accelerates tissue repair, supporting faster healing from workouts, injuries, and routine physical stress. Beneficial for athletes and active individuals.
Safety & Considerations
Peptide therapy should always be guided by a qualified medical provider. Because peptides vary in formulation and delivery, proper prescribing, dosing, and administration are essential.
Not every peptide is appropriate for every patient, and some may not be recommended based on individual health factors or current medications. For this reason, peptide use at Health by Design is determined on a case-by-case basis following a medical consultation.
As with any therapeutic option, patients are educated on proper use, potential side effects, and realistic outcomes to support safe and informed care.
Ready to See if Peptide Therapy Is Right for You?
If you’re experiencing low energy, difficulty building or maintaining muscle, increased body fat, poor sleep, or slower recovery, peptide therapy with Semorelin and Ipamorelin may help restore balance.
Request an appointment online or contact our Chesterfield, MO office today.
Frequently Asked Questions
How soon will I notice results?
Most patients begin noticing improvements in sleep quality, recovery, and energy within 4–6 weeks. Body composition changes and deeper metabolic benefits typically develop over 3–6 months of consistent use.
How are the peptides administered?
Both Sermorelin and Ipamorelin are given through very small subcutaneous injections, usually in the abdomen. The process is quick, comfortable, and easy for most patients to self-administer at home.
Can peptides support weight loss?
Yes, peptides can enhance metabolism, support lean muscle development, improve sleep, and increase energy levels, all of which can help with weight-loss efforts. The best results occur when peptide therapy is part of a comprehensive health plan
Can I combine peptide therapy with other treatments?
Absolutely. Peptides work well alongside functional weight-loss programs, hormone optimization, and longevity-focused therapies. Your provider will design a personalized plan based on your goals.